Saw this question a few times so thought I share it here (I tweeted about this a few weeks ago). If you are having problems installing Wireshark 1.8.1 on OSX 10.8, you need to know that OSX 10.8 does not come with X11 pre-installed. As such, you need to find other X11 libraries such as XQuartz. Google for XQuartz, get the latest version and install it. Once that's done, you are back to being a packet ninja.